Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro) (By similarity). Binds NADPH and has NADPH-dependent aldoketoreductase activity (By similarity). It was built in 1856, and has had wings and other.
#322 SKULL AND BONES FULL#
Enhances KCNB2 channel activity (By similarity). The Skull and Bones Tomb is a bare, symmetrical, sandstone building and the quintessential Yale tombimposing, windowless, and full of secrets.
Modulates the functional properties of KCNA5 (By similarity). Skull and Bones: Americas Most Powerful and Mysterious Secret Society. Promotes KCNA4 channel closure (PubMed: 7649300, PubMed: 11825900). Skull and Bones: Americas Most Powerful and Mysterious Secret Society.Skulls and Bones: A Guide to the Skeletal Structures and Behavior of North American Mammals.
Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore (PubMed: 7649300, PubMed: 11825900). Skull and Bones is an undergraduate senior secret student society at Yale University in New Haven.
Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (PubMed: 7649300, PubMed: 11825900).
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